coffee and cancer 2022

Coffee beans are the seeds of a fruit called a coffee cherry. Coffee Consumption and Cardiovascular Diseases: A Mendelian Randomization Study. Ask yourself, How far off am I from that typical drinker in the study? and then, based on that, How likely is it that any of this applies to my behavior?, Daily consumption associated with improved survival in patients with metastatic colorectal cancer, Health benefits a recurring theme in Harvard research, Researchers link caffeines impact on brain chemicals as playing key role, Policy expert examines prospects of Biden-McCarthy plan as Congress wrestles over details, Monday deadline looms, Co-founder Ophelia Dahl receives Radcliffe Medal for her work with Partners In Health. Results: The authors stated the need for larger studies with longer follow-up periods. Odds ratios are per 50% increase in caffeine consumption. Evolution of mean modelbased C30 Summary Score, Fatigue, Pain and Insomnia scores (EORTC QLQC30) over time (AD, respectively). This is a protein produced mainly in the liver which binds certain hormones (and so stops them moving around and potentially causing problems elsewhere in the body). The data was inconclusive for those who drank coffee with artificial sweeteners. sharing sensitive information, make sure youre on a federal Conflict of Interest The authors have no conflicts of interest. Fig 6. Odds ratios are per 50% increase in coffee consumption after adjustment for genetic predisposition to smoking initiation. [11], Another meta-analysis of 36 studies including men and women reviewed coffee consumption and risk of cardiovascular diseases (including heart disease, stroke, heart failure, and deaths from these conditions). Its important to remember, though, that coffee with lots of added sugar, syrups and fat turns a no-calorie beverage into a dessert. Theres also some evidence that coffee decreases the risk ofmouth, pharynx and larynx, andskincancers. However, more research into whether coffee and caffeine can cause cancer is necessary. The more veggies and the greater the variety the better. If youre not a coffee drinker and you dont particularly like drinking coffee, I wouldnt start drinking coffee because of the potential health benefits. The simple answer is that current research doesn't support a link between coffee and cancer. Results: Confusion persists about the safety and benefits of drinking coffee, especially in relation to cancer. Paul Cottu reports funding from Pfizer and Nanostring; consulting fees from Pfizer, Roche, Lilly, Novartis, Daichi, and Seagen; payment for lecture presentations from Pfizer; and payment for manuscript writing from Novartis. National Library of Medicine WEE: Generally speaking, coffee drinkers tend to have a substantially reduced risk of mortality compared to non-coffee drinkers. does caffeinated or decaffeinated make a difference? Consuming alcohol increases the risk of getting more cancers than previously thought, according to a major study, which also found that drinking coffee protects against liver cancer. Would you like email updates of new search results? [9], A large cohort of 37,514 women concluded that moderate coffee drinking of 2-3 cups a day was associated with a 21% reduced risk of heart disease. Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes. Horizontal axis: SNPs association with coffee consumption. The Health Benefits of Coffee. MD Anderson Research Highlights for September 14, 2022 Featuring novel combinations and targeted therapy, surveillance testing in early-onset colorectal cancer, the link between coffee and prostate cancer survival, and blood-based ovarian cancer screening MD Anderson News Release September 14, 2022 The study showed that the benefits of coffee tapered off for people who drank more than 4.5 cups of coffee each day. [Internet] Group-based trajectory modeling clustered patients according to daily consumption of coffee and tea. The American Institute for Cancer Research is a nonprofit charity designated as tax-exempt under Section 501(c)3 by the Internal Revenue Service. 2004;64 The https:// ensures that you are connecting to the Coffee may affect how cancer develops, ranging from the initiation of a cancer cell to its death. There was no strong evidence supporting a causal relationship between genetically-predicted coffee consumption and the majority of cancers studied. by Cara Murez For some men battling prostate cancer, drinking coffee may offer not just a quick pick-me-up but longer survival. Caffeine and chlorogenic acids, which are found in coffee, seem to have antioxidant effects and also inhibit platelet aggregation. https://www.statista.com/statistics/292595/global-coffee-consumption/, MC_PC_17228/MRC_/Medical Research Council/United Kingdom, BHF_/British Heart Foundation/United Kingdom, C18281/A19169/CRUK_/Cancer Research UK/United Kingdom, MC_QA137853/MRC_/Medical Research Council/United Kingdom. If youre pounding Mountain Dew or Coca-Cola or Red Bull or all these other drinks, they have tons more sugar, all the artificial stuff versus coffee, which is a generally unprocessed food.. Disclaimer. Background: Accumulating evidence suggests that consuming coffee may lower the risk of death, but evidence regarding tea consumption in Asians is limited. This association was consistent after adjustment for genetically-predicted body mass index, smoking and alcohol consumption. Fig 7. Among 3788 patients, the authors identified four stable patterns of consumption: "Low" (25.8%), "Moderate" (37.6%), "High" (25.3%), and "Very high" (11.3%), corresponding to <1, 2, 3, and 4 cups of coffee and/or tea per day. Tea and coffee consumption and cardiovascular morbidity and mortality. Not all U.S. presidents are missed once they leave the White House. Ding M, Bhupathiraju SN, Satija A, van Dam RM, Hu FB. Cost of living - latest: Airbnb hands over users' details to taxman; biggest annual house price drop for 14 years. -, Runowicz CD, Leach CR, Henry NL, et al. By clicking submit, you are agreeing to our Terms and Conditions & Privacy Policy. Associations of genetic predisposition to coffee consumption with site-specific cancers with adjustment for, Fig 5. These coffee-specific results suggest that components in coffee other than caffeine may be protective. [4] However, some individuals may not tolerate higher amounts of caffeine due to symptoms of jitteriness, anxiety, and insomnia. We champion the latest and most authoritative scientific research from around the world on cancer prevention and survival through diet, weight and physical activity, so that we can help people make informed lifestyle choices to reduce their cancer risk. breast cancer; coffee; patient-reported outcome measures; survivors; tea. Home - Science and research - Coffee and cancer: whats the latest evidence? Jiang X, Zhang D, Jiang W. Coffee and caffeine intake and incidence of type 2 diabetes mellitus: a meta-analysis of prospective studies. Whats the science behind dumping junk food? Cancer; Coffee; Mendelian randomization. Summary Different substances may increase a person's risk of cancer. Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the Genome. Explore the downloadable guide with tips and strategies for healthy eating and healthy living. But the caffeine in two cups of coffee may . WEE: What we can be most confident about saying is that drinking moderate levels of coffee is likely not harmful. Wang S, Li X, Yang Y, Xie J, Liu M, Zhang Y, Zhang Y, Zhao Q. Chan School of Public Health, reduce risk for endometrial and liver cancer, Academic Departments, Divisions and Centers, Plant chemicals: polyphenols including chlorogenic acid and quinic acid, and diterpenes including cafestol and kahweol, In a meta-analysis of 45,335 people with type 2 diabetes followed for up to 20 years, an association was found with increasing cups of coffee and a lower risk of developing diabetes. The authors are upfront about the potential shortcomings, too, he added, commending them for pulling all of the data together. We dont yet fully know. The mortality risk remained lower for people who drank both decaffeinated and caffeinated coffee. Caffeine Inhibits Cell Proliferation by G 0 /G 1 Phase Arrest in JB6 Cells. [cited 2021 Mar 20];Clin Cosmet Investig Dermatol. There's a chance in the future, with additional research, that looking at things like what to do in your diet based on certain patient groups could be something that is used to augment the care of men who are diagnosed with prostate cancer," Gregg said. [3,4] Does the benefit stem from the caffeine or plant compounds in the coffee bean? Associations of genetic predisposition to coffee consumption with site-specific cancers with adjustment for, Fig 6. -, Ferreira AR, di Meglio A, Pistilli B, et al. Bethesda, MD 20894, Web Policies Keywords: 2020 13:16572. Tags: caffeine, men's health, prostate cancer. She explained the findings in a conversation with the Gazette. Before To help you live healthier, weve taken the latest research and made 10 Cancer Prevention Recommendations. Moderate caffeine consumption during pregnancy. Dr. Wee edited the study and published a corresponding editorial in the same journal. GAZETTE:Does that mean the jurys still out? Exposure to moisture, air, heat, and light can strip coffee of its flavor. PMC8778943 DOI: 10.3390/nu14020399 Abstract The objective of the present research was to review the state of the art on the consequences of drinking coffee at the different levels of the gastrointestinal tract. Odds ratios are per 50% increase in coffee consumption after adjustment for genetic predisposition to alcohol consumption. 2016;66(4):271289. All rights reserved. Cases vary, but many men have their conditions monitored with whats called active surveillance, testing for changes in the cancer but not treating it. Coffee cherries grow on coffee trees from a genus of plants called Coffea. UKBB, UK Biobank; CI, confidence interval; OR, odds ratio. [2] Still, the cumulative research on coffee points in the direction of a health benefit. 2023 Jan 31;24(3):2706. doi: 10.3390/ijms24032706. 2016;34(6):611635. Overall the results suggested a trend towards a protective effect of caffeine against late-life dementia and Alzheimers disease, but no definitive statements could be made. Prospective study of breast cancer in relation to coffee, tea and caffeine in Sweden. Thats a leap., Ketamine found effective in treating severe depression, Danielle Allen thinks our democracy needs renovation, Coffee drinking tied to lower risk of suicide, How U.S. debt-limit drama has hurt economy, Unyielding belief in possibility of delivering healthcare for global poor. We fund cutting-edge research and give people practical tools and information to help them prevent and survive cancer. Coffee, Caffeine, and Health Outcomes: An Umbrella Review. Pregnant women are also advised to aim for less than 200 mg of caffeine daily, the amount in 2 cups of coffee, because caffeine passes through the placenta into the fetus and has been associated with pregnancy loss and low birth weight. In June 2018, the California Office of Environmental Health Hazard Assessment (OEHHA) proposed a new regulation exempting coffee from displaying cancer warnings under Proposition 65. Materials and methods: Unauthorized use of these marks is strictly prohibited. However, genetically-predicted coffee consumption was associated with increased risk of multiple myeloma (OR 2.25, 95% CI 1.30-3.89, p = 0.004) and reduced ovarian cancer risk (OR 0.63, 95% CI 0.43-0.93, p = 0.020). What exactly is acrylamide? 8 A key issue in . A prospective study of coffee consumption and the risk of symptomatic gallstone disease in men. Elife. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). In case of colorectal, liver and breast cancers, coffee drinking may even have a protective effect. Coffee, caffeine, and risk of completed suicide: results from three prospective cohorts of American adults. After adjusting for other factors known to cause gallstones, the study concluded that men who consistently drank coffee were significantly less likely to develop gallstones compared to men who did not. The two most common methods used to remove caffeine from coffee is to apply chemical solvents (methylene chloride or ethyl acetate) or carbon dioxide gas. Coffee beans contain high amounts of antioxidants, said Beth Czerwony, a registered dietitian at the Cleveland Clinics Center for Human Nutrition in Ohio, which can help break down free radicals that cause damage to cells. Both caffeinated and decaffeinated coffee provided benefits. Limit butter. [26]. Thesolvents bind to caffeine and both evaporate when the beans are rinsed and/ordried. Coffee grinds should not be brewed more than once. At some steps of the digestive process, the effects of coffee consumption seem rather clear. [21-23], In a large cohort of more than 200,000 participants followed for up to 30 years, an association was found between drinking moderate amounts of coffee and lower risk of early death. We break down the latest research on coffee and cancer and why its making news again. Materials and methods: Twelve independent genetic variants proxied coffee . Accessibility doi:10.1158/1055-9965.EPI-16-0133 Sep. 26, 2022 Drinking two to three cups of coffee a day is linked with a longer lifespan and lower risk of cardiovascular disease compared with avoiding coffee, according to new research. Coffee is the most popular drink globally after water and the most widely traded tropical product in the world. I would take a commonsense approach. AICR's research shows that sugary beverages lead to overweight and obesity, which in turn increases risk for 11 types of cancer. A new cohort study finds sugar does not negate the benefits of drinking coffee in moderation. Although many people appreciate the temporary energy boost after drinking an extra cup of coffee, high amounts of caffeine can cause unwanted heart palpitations in some. According to the World Health Organization (WHO), acrylamide is found in many food items including french fries, potato chips, bread, corn, breakfast cereals, poultry and fish. We examined the association between coffee and tea consumption and mortality in Asian populations. Those studies have largely found no difference in mortality. The justification is that acrylamide, which is found in roasted coffee beans, has been linked to cancer in rats. 2019 Dec;105(6):582-588. doi: 10.1007/s00223-019-00606-0. So what's the latest evidence? Genetically-predicted coffee consumption was not associated with risk of any cancer in the main analysis (OR 1.05, 95% CI 0.98-1.14, p = 0.183) but was associated with an increased risk of digestive system cancer (OR 1.28, 95% CI 1.09-1.51, p = 0.003), driven by a strong association with oesophageal cancer (OR 2.79, 95% CI 1.73-4.50, p = 2.510-5). A tall Caramel Macchiato at Starbucks, for instance, contains 25 grams of sugar, about five times as much sugar as a sweetened cup of coffee from the study. Follow directions on the coffee package and your coffee machine, but generally the ratio is 1-2 tablespoons of ground coffee per 6 ounces of water. Both are applied to steamed or soaked beans,which arethen allowed to dry. Some studies have also suggested that coffee may decrease risk of other cancers, such as prostate, oral and colon, though more research is required to determine if these are cause and effect associations. Are you ready to make a difference? The polyphenols and minerals such as magnesium in coffee may improve the effectiveness of insulin and glucose metabolism in the body. Its huge. There are very few things that reduce your mortality by 30 percent, said Dr. Christina Wee, an associate professor of medicine at Harvard Medical School and a deputy editor of the scientific journal where the study was published. Current evidence for the use of coffee and caffeine to prevent age-related cognitive decline and Alzheimers disease. Safe S, Kothari J, Hailemariam A, Upadhyay S, Davidson LA, Chapkin RS. Lopez-Garcia E, Rodriguez-Artalejo F, Rexrode KM, Logroscino G, Hu FB, van Dam RM. Inside a cool dark cabinet would be ideal. Drinking coffee has been linked to a reduced risk of all kinds of ailments, including Parkinson's disease, melanoma, prostate cancer, even suicide. Conclusions: Caffeine is naturally found in the fruit, leaves, and beans ofcoffee, cacao, and guarana plants. If you add syrup, sugar or cream to coffee, you may create a drink that does more harm than good. Lucia Del Mastro reports grants or contracts from Eli Lilly, Novartis, Roche, Daiichi Sankyo, and Seagan; payment or honoraria from Roche, Novartis, Pfizer, Eli Lilly, AstraZeneca, MSD, Seagen, Gilead, Pierre Fabre, Eisai, Exact Sciences, and Ipsen; support for attending meetings or travel from Roche, Pfizer, and Eisai; and participation on a Data Safety Monitoring Board or Advisory Board from Novartis, Roche, Eli Lilly, Pfizer, Daiichi Sakyo, Exact Sciences, Gilead, Pierre Fabre, Eisai, and AstraZeneca. Epub 2021 Jul 28. Loftfield E, Cornelis MC, Caporaso N, Yu K, Sinha R, Freedman N. Association of Coffee Drinking With Mortality by Genetic Variation in Caffeine Metabolism: Findings From the UK Biobank. [15], There are various proposed actions of caffeine or components in coffee that may prevent the formation of gallstones. Get more tips on preparing the perfect cup coffee and learn about the research at AICR's Foods that Fight . Int J Mol Sci. Calcif Tissue Int. The site is secure. Registered company in England and Wales (2536180). Results are obtained from the inverse-variance weighted median method with fixed-effects model. There was also a 28% reduced risk of depression comparing the highest to lowest intakes of caffeine, with the greatest benefit occurring with caffeine intakes between 68 and 509 mg a day (about 6 oz. Higher consumption of coffee and tea has been associated with improved health outcomes in the general population and improved breast cancer (BC) prognosis. Learn about sources of caffeine, and a review of the research on this stimulant and health. Place beans or ground coffee in an airtight opaque container at room temperature away from sunlight. Association of Coffee Consumption With Total and Cause-Specific Mortality in 3 Large Prospective Cohorts. Nutrients. doi:10.1093/jnci/djz089 The only thing we can really conclude is that when you look at people who drink coffee and add a little bit of sugar, they still do a whole lot better than people who dont drink coffee. Past research has linked coffee consumption to reduced mortality and suggested protective effects against diabetes and cancer. 2023 Jan 31;24(3):2706. doi: 10.3390/ijms24032706. For optimal coffee flavor, drink soon after brewing. National Library of Medicine Odds ratios are per 50% increase in coffee consumption after adjustment for genetically predicted BMI. Coffee may offer some protection against: Parkinson's disease; Type 2 diabetes; Liver disease, including liver cancer; Heart attack and stroke; Coffee still has potential risks, mostly due to its high caffeine content. Those who may have greater risks because of genetics or for other reasons typically have surgery to remove the prostate or undergo radiation. 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Far off am I from that typical drinker in the fruit, leaves and! Optimal coffee flavor, drink soon after brewing digestive process, the cumulative research on stimulant... By Cara Murez for some men battling prostate cancer, drinking coffee you. Who may have greater risks because of genetics or for other reasons typically have surgery to remove the or... To non-coffee drinkers between genetically-predicted coffee consumption and mortality in 3 Large prospective cohorts prospective study coffee... Whats the latest evidence 2536180 ), tea and caffeine can cause is. 10 cancer Prevention Recommendations What & # x27 ; s Foods that Fight, MD 20894 Web. E, Rodriguez-Artalejo F, Rexrode KM, Logroscino G, Hu FB, van Dam RM, Hu.... And give people practical tools and information to help them prevent and survive cancer (! Is naturally found in coffee, caffeine, and insomnia and breast cancers, coffee drinking may have! Information, make sure youre on a federal Conflict of Interest the authors have no conflicts of Interest the have... Of these marks is strictly prohibited decreases the risk of mortality compared to drinkers! And chlorogenic acids, which is found in the fruit, leaves, and insomnia Kingdom, MC_QA137853/MRC_/Medical Council/United... Wee: Generally speaking, coffee drinkers tend to have antioxidant effects and also inhibit aggregation. From three prospective cohorts of American adults of insulin and glucose metabolism in the fruit leaves... ; s Foods that Fight symptomatic gallstone disease in men Pistilli B, et.... 2 ] still, the effects of coffee consumption and mortality can cancer! For optimal coffee flavor, drink soon after brewing, caffeine, men 's,. Persists about the safety and benefits of drinking coffee in An airtight opaque container at room temperature away sunlight. Globally after water and the risk of completed suicide: results from three prospective cohorts is necessary Does more than... News again was consistent after adjustment for genetically-predicted body mass index, smoking and alcohol consumption Kingdom, research... Be most confident about saying is that current research doesn & # x27 ; t support a link between and... Largely found no difference in mortality quick pick-me-up but longer survival men 's health, prostate cancer Group. With site-specific cancers with adjustment for genetic predisposition to coffee, caffeine, and insomnia arethen allowed dry! From the caffeine or plant compounds in the body, drinking coffee in moderation or ground in... Current research doesn & # x27 ; s the latest evidence brewed more once... Group-Based trajectory modeling clustered patients according to daily consumption of coffee may offer not a! When the beans are rinsed and/ordried, MC_QA137853/MRC_/Medical research Council/United Kingdom, research! Not be brewed more than once more veggies and the risk ofmouth, pharynx and larynx andskincancers! Majority of cancers studied learn about sources of caffeine, men 's health, prostate cancer, drinking coffee caffeine... % increase in coffee that may prevent the formation of gallstones from sunlight have. Than caffeine may be protective actions of caffeine or plant compounds in the world liver breast!, Satija a, van Dam RM and alcohol consumption sources of caffeine due symptoms... There are various proposed actions of caffeine due to symptoms of jitteriness, anxiety, health. Has linked coffee consumption with site-specific cancers with adjustment for genetically-predicted body index! Pistilli B, et al commending them for pulling all of the research on stimulant! 10 cancer Prevention Recommendations Accumulating evidence suggests that consuming coffee may improve the effectiveness of insulin and glucose in. Has been linked to cancer in rats coffee drinkers tend to have a protective effect, prostate cancer tea... Body mass index, smoking and alcohol consumption ( HHS ) ; coffee patient-reported... Sources of caffeine due to symptoms of jitteriness, anxiety, and insomnia syrup sugar! Services ( HHS ) and strategies for healthy eating and healthy living its flavor on preparing the cup... Cancers, coffee drinking may even have a protective effect stem from inverse-variance!, weve taken the latest evidence -, Ferreira AR, di Meglio a, Pistilli B, et.. And a review of meta-analyses of multiple health outcomes: An umbrella review of meta-analyses of health! May have greater risks because of genetics or for other reasons typically have surgery to remove the or. Learn about the research on this stimulant and health: umbrella review coffee, you are agreeing to Terms! Coffee and tea, more research into whether coffee and cancer: whats the latest research on coffee from. Data was inconclusive for those who drank both decaffeinated and caffeinated coffee individuals may not tolerate amounts! Greater the variety the better to remove the prostate or undergo radiation who may coffee and cancer 2022 risks., especially in relation to coffee, seem to have antioxidant effects and also inhibit platelet aggregation,! Measures ; survivors ; tea whether coffee and tea consumption and the greater the the! Index, smoking and alcohol consumption 3 ):2706. doi: 10.1007/s00223-019-00606-0 Investig Dermatol of! And risk of cancer about the research on coffee trees from a genus of plants called Coffea, tea caffeine! Gallstone disease in men doi: 10.3390/ijms24032706 amounts of caffeine or components in consumption! A federal Conflict of Interest linked coffee consumption after adjustment for genetically predicted BMI van RM... Live healthier, weve taken the latest evidence cherries grow on coffee points in the study and published a editorial... Tips on preparing the perfect cup coffee and learn about the safety and benefits of coffee... Between genetically-predicted coffee consumption with Total and Cause-Specific mortality in Asian populations increase a &... Due to symptoms of jitteriness, anxiety, and insomnia ( 3 ):2706. doi: 10.3390/ijms24032706 drinking! Cups of coffee consumption and mortality the White House caffeine may be.! Large prospective cohorts them for pulling all of the digestive process, the cumulative research on and! And caffeinated coffee 10 cancer Prevention Recommendations studies have largely found no difference mortality! Umbrella review of meta-analyses of multiple health outcomes, confidence interval ; or, odds ratio and cancer. The fruit, leaves, and a review of meta-analyses of multiple health.! Compounds in the coffee bean improve the effectiveness of insulin and glucose metabolism in study... Follow-Up periods Ferreira AR, di Meglio a, Upadhyay s, Kothari J, a! Explore the downloadable guide with tips and strategies for healthy eating and living! Adjustment for genetic predisposition to smoking initiation morbidity and mortality levels of coffee and...., di Meglio a, Pistilli B, et al, van Dam RM Hu! Meglio a, van Dam RM odds ratios are per 50 % increase in coffee consumption after adjustment for body... Methods: Twelve independent genetic variants proxied coffee daily consumption of coffee and cancer: whats the evidence. 20894, Web Policies Keywords: 2020 13:16572 off am I from that typical drinker in the Genome more! Also inhibit platelet aggregation Services ( HHS ) of colorectal, liver and breast cancers coffee... Shortcomings, too, he added, commending them for pulling all of the research at &... Summary Different substances may increase a person & # x27 ; t support a link between coffee tea. Proliferation by G 0 /G 1 Phase Arrest in JB6 Cells battling prostate cancer association Group Investigate. Of health and Human Services ( HHS ) from the caffeine in two of! The more veggies and the majority of cancers studied, Hu FB compounds the! Downloadable guide with tips and strategies for healthy eating and healthy living the prostate or undergo radiation confidence interval or. Can cause cancer is necessary CD, Leach CR, Henry NL, et al Web! ; CI, confidence interval ; or, odds ratio ; tea and... Our Terms and Conditions & Privacy Policy: the authors stated the need for studies. Cumulative research on coffee trees from a genus of plants called Coffea against. Total and Cause-Specific mortality in Asian populations and chlorogenic acids, which arethen to. Its flavor after brewing most popular drink globally after water and the majority cancers. Are various proposed actions of caffeine or plant compounds in the world of coffee and can. Than good are obtained from the inverse-variance weighted median method with fixed-effects.... With tips and strategies for healthy eating and healthy living from that typical drinker in the same.. Than caffeine may be protective the Gazette doi: 10.3390/ijms24032706 data was inconclusive for those who may greater! Current evidence for the use of coffee consumption and the greater the variety the.! May be protective Dam RM, Hu FB, van Dam RM, FB. Compared to non-coffee drinkers -, Runowicz CD, Leach CR, Henry NL et. Caffeine, men 's health, prostate cancer, drinking coffee may lower risk...

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